Microvillus inclusion disease associated with coarctation of the aorta and bicuspid aortic valve

J Clin Gastroenterol. 2008 Apr;42(4):400-3. doi: 10.1097/01.mcg.0000225632.07039.b6.

Abstract

Microvillus inclusion disease is a life-threatening diarrheal disorder of infancy characterized by the presence of microvillus inclusions within the intestinal epithelium. We report a case of a neonate with microvillus inclusion disease that was associated with coarctation of the aorta and bicuspid aortic valve, cardiac malformations within the spectrum of left ventricular outlet tract obstruction. Possible links between the intestinal and cardiac phenotypes are discussed.

Publication types

  • Case Reports

MeSH terms

  • Aortic Coarctation / complications*
  • Aortic Coarctation / diagnostic imaging
  • Aortic Valve / abnormalities*
  • Aortic Valve / diagnostic imaging
  • Diagnosis, Differential
  • Diarrhea / etiology*
  • Diarrhea / pathology
  • Echocardiography
  • Humans
  • Infant, Newborn
  • Intestinal Mucosa / ultrastructure*
  • Male
  • Microscopy, Electron
  • Microvilli
  • Ventricular Outflow Obstruction / complications*
  • Ventricular Outflow Obstruction / congenital
  • Ventricular Outflow Obstruction / diagnostic imaging