Abstract
Small noncoding RNAs have emerged as potent regulators of gene expression at both transcriptional and posttranscriptional levels. Recently, a class of small RNAs that interact with Piwi proteins has been discovered in the mammalian germ line and Drosophila. These Piwi-interacting RNAs (piRNAs) represent a distinct small RNA pathway.
MeSH terms
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Animals
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Argonaute Proteins
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Drosophila
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Drosophila Proteins / metabolism
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Epigenesis, Genetic
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Gene Expression Regulation, Developmental
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Germ Cells / cytology
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Germ Cells / metabolism*
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Mice
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Peptide Initiation Factors / metabolism
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Protein Biosynthesis
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Proteins / metabolism*
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RNA Stability
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RNA, Untranslated / genetics
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RNA, Untranslated / metabolism*
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RNA-Induced Silencing Complex
Substances
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AGO3 protein, Drosophila
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Argonaute Proteins
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Drosophila Proteins
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Peptide Initiation Factors
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Piwil1 protein, mouse
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Proteins
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RNA, Untranslated
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RNA-Induced Silencing Complex
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aub protein, Drosophila
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piwi protein, Drosophila