Addiction and arousal: alternative roles of hypothalamic peptides

J Neurosci. 2006 Oct 11;26(41):10372-5. doi: 10.1523/JNEUROSCI.3118-06.2006.

Abstract

The importance of the lateral hypothalamus in the regulation of reward and motivation has long been recognized. However, the neuronal network involved in such a hypothalamic regulation of reward remains essentially unknown. Recently, hypocretin-containing neurons, a group of hypothalamic neurons known to be associated with the stability of arousal, have emerged as important structures in the control of brain reward function. This review summarizes a Mini-Symposium presented at the 2006 Annual Meeting of the Society for Neuroscience.

Publication types

  • Review

MeSH terms

  • Animals
  • Arousal / physiology*
  • Behavior, Addictive / metabolism*
  • Humans
  • Hypothalamic Area, Lateral / metabolism
  • Hypothalamus / metabolism*
  • Neuropeptides / metabolism*

Substances

  • Neuropeptides