Please hold--the next available exon will be right with you

Nat Struct Mol Biol. 2006 May;13(5):385-6. doi: 10.1038/nsmb0506-385.

Abstract

A major challenge in gene expression is to understand how precursor messenger RNA (pre-mRNA) processing events are integrated with transcription. A recent study suggests that distant exons in nascent RNA are held together during transcription, promoting accurate splicing independent of intron fate.

Publication types

  • News

MeSH terms

  • Exons / genetics*
  • Introns / genetics
  • RNA Polymerase II / metabolism
  • RNA Precursors / genetics
  • RNA Precursors / metabolism
  • RNA Splicing / genetics*
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • Transcription, Genetic

Substances

  • RNA Precursors
  • RNA, Messenger
  • RNA Polymerase II