New insights into the pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy

Obesity (Silver Spring). 2006 Feb;14 Suppl 1(0 1):34S-40S. doi: 10.1038/oby.2006.280.

Abstract

Insulin resistance plays a major role in the pathogenesis of type 2 diabetes, yet despite much effort, the underlying factors that are responsible for it are poorly understood. In this review, we focus on some recent advances in our understanding of the pathogenesis of insulin resistance in humans that have been made using magnetic resonance spectroscopy.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Blood Glucose / metabolism
  • Energy Intake / physiology
  • Fatty Acids / metabolism
  • Humans
  • Insulin Resistance / physiology*
  • Magnetic Resonance Spectroscopy / methods*
  • Muscle, Skeletal / metabolism*
  • Obesity / metabolism*
  • Obesity / physiopathology

Substances

  • Blood Glucose
  • Fatty Acids