New images evoke FAScinating questions

Chem Biol. 2006 Apr;13(4):349-51. doi: 10.1016/j.chembiol.2006.04.001.

Abstract

Two recent papers in Science reported the X-ray structures of the large, organizationally distinct animal and fungal fatty acid synthases at 5 A. These new structural insights have unexpected implications for enzyme function for the other "iterative" and "assembly line" megasynthases.

Publication types

  • Comment
  • Comparative Study

MeSH terms

  • Animals
  • Catalytic Domain
  • Crystallography, X-Ray
  • Fatty Acid Synthases / chemistry*
  • Fungi / enzymology
  • Models, Molecular
  • Molecular Structure
  • Protein Structure, Quaternary
  • Protein Structure, Tertiary

Substances

  • Fatty Acid Synthases