Most endodontists use ultrasonic instruments for retrograde root-end cavity preparations even though they have been found to produce cracks. In this laboratory study, thirty-six randomly chosen roots had root-end cavity preparations made with the Waterlase laser and only one questionable intra-canal crack was found. It was concluded that the Waterlase laser when used to make endodontic root-end cavity preparations produces either no cracks, or a very low percentage (2.8%) of cracks.