Myocardial infarction after taking zolmitriptan

Yale J Biol Med. 2005 May;78(3):147-50.

Abstract

We report the case of a patient with mild non-obstructive coronary artery disease who sustained an inferior wall myocardial infarction shortly after taking zolmitriptan as abortive therapy for migraine headaches. A Medline search was performed to review all reported cases of myocardial infarction related to migraine therapy with zolmitriptan and related medications. Zolmitriptan may cause myocardial infarction (MI) even in the absence of significant coronary artery disease.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Coronary Artery Disease / complications
  • Coronary Artery Disease / drug therapy
  • Female
  • Humans
  • Migraine Disorders / complications
  • Migraine Disorders / drug therapy*
  • Myocardial Infarction / chemically induced*
  • Oxazolidinones / adverse effects*
  • Oxazolidinones / therapeutic use
  • Serotonin Receptor Agonists / adverse effects
  • Tryptamines / adverse effects*
  • Tryptamines / therapeutic use

Substances

  • Oxazolidinones
  • Serotonin Receptor Agonists
  • Tryptamines
  • zolmitriptan