Abstract
All the approved chemotherapeutic drugs for the treatment of HBV hepatitis are nucleoside analogs targeting on HBV DNA polymerase. Drugs targeting on other viral unique targets are needed. A new class of chemicals with novel action against HBV replication was discovered. A brief description of their mode of action is given.
MeSH terms
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Antiviral Agents* / chemical synthesis
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Antiviral Agents* / pharmacology
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DNA, Viral / biosynthesis
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Drug Design*
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Hepatitis B virus / drug effects*
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Hepatitis B virus / genetics
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Hepatitis B virus / metabolism
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Lignans
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Microbial Sensitivity Tests
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Nucleic Acid Synthesis Inhibitors
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Virus Replication / drug effects*
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Xanthines / pharmacology
Substances
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Antiviral Agents
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DNA, Viral
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Lignans
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Nucleic Acid Synthesis Inhibitors
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Xanthines
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helioxanthin