Solitary fibrous tumor of the larynx: a case report and review of the literature

Arch Pathol Lab Med. 2006 Feb;130(2):213-6. doi: 10.5858/2006-130-213-SFTOTL.

Abstract

Solitary fibrous tumors are relatively rare mesenchymal neoplasms that were originally described as pleural- or peritoneal-based lesions. Although they were considered a form of mesothelioma, subsequent investigation failed to reveal mesothelial differentiation. Characterization of their histologic and immunohistochemical features, as well as identification in a multitude of nonmesothelial-based locations has further served to distinguish these lesions from the more diffuse and aggressive mesothelioma. Reports of solitary fibrous tumor in the larynx are extremely rare. We report a case of solitary fibrous tumor of the larynx in a 38-year-old man.

Publication types

  • Case Reports

MeSH terms

  • 12E7 Antigen
  • Adult
  • Antigens, CD / analysis
  • Antigens, CD34 / analysis
  • Biomarkers, Tumor / analysis
  • Cell Adhesion Molecules / analysis
  • Fibroma / chemistry
  • Fibroma / pathology*
  • Fibroma / surgery
  • Humans
  • Laryngeal Neoplasms / chemistry
  • Laryngeal Neoplasms / pathology*
  • Laryngeal Neoplasms / surgery
  • Male
  • Treatment Outcome

Substances

  • 12E7 Antigen
  • Antigens, CD
  • Antigens, CD34
  • Biomarkers, Tumor
  • CD99 protein, human
  • Cell Adhesion Molecules