Abstract
We performed a double-blinded retrospective cohort study to determine whether endometrial expression of mouse ascites Golgi mucin in a natural, unmedicated cycle predicts subsequent IVF-ET outcome among women with prior IVF-ET failure and poor pre-embryo quality. We found a statistically significant decrease in clinical pregnancy rate among women with abnormal mouse ascites Golgi expression, a test which was found to have high positive predictive value for failed IVF-ET.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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ABO Blood-Group System / immunology
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ABO Blood-Group System / metabolism*
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Adult
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Antibodies
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Biomarkers
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Biopsy
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Cohort Studies
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Embryo Implantation
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Embryo Transfer*
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Endometrium / cytology
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Endometrium / metabolism*
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Epitopes / immunology
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Epitopes / metabolism
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Female
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Fertilization in Vitro*
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Humans
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Mucins / immunology
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Mucins / metabolism*
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Predictive Value of Tests
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Pregnancy
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Pregnancy Outcome
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Retrospective Studies
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Treatment Failure
Substances
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ABO Blood-Group System
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Antibodies
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Biomarkers
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Epitopes
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Mucins