Low prevalence of premature ovarian failure in women given reduced-intensity conditioning regimens for hematopoietic stem-cell transplantation

Yee Chung Cheng; Rima M Saliba; Gabriela Rondón; Sergio A Giralt; Karen H Lu; Diane C Bodurka; David M Gershenson; Richard E Champlin; Naoto T Ueno

Low prevalence of premature ovarian failure in women given reduced-intensity conditioning regimens for hematopoietic stem-cell transplantation

Haematologica. 2005 Dec;90(12):1725-6.

Authors

Yee Chung Cheng, Rima M Saliba, Gabriela Rondón, Sergio A Giralt, Karen H Lu, Diane C Bodurka, David M Gershenson, Richard E Champlin, Naoto T Ueno

PMID: 16330461

Abstract

A survey was done to determine the prevalence of premature ovarian failure among female transplant patients. Within the 109 patients who replied, premature ovarian failure was found to be less common among women given reduced-intensity conditioning regimens (37.5%) than among those given high-dose conditioning regimens (79%) for hematopoietic stem-cell transplantation (p=0.007).

Publication types

Comparative Study
Letter

MeSH terms

Adolescent
Adult
Antineoplastic Agents / administration & dosage
Antineoplastic Agents / adverse effects*
Female
Follow-Up Studies
Hematopoietic Stem Cell Transplantation*
Humans
Prevalence
Primary Ovarian Insufficiency / epidemiology
Primary Ovarian Insufficiency / etiology*
Radiation Injuries / epidemiology
Radiation Injuries / etiology
Surveys and Questionnaires
Transplantation Conditioning / adverse effects*
Transplantation Conditioning / methods
Transplantation, Autologous
Transplantation, Homologous
Whole-Body Irradiation / adverse effects

Substances

Antineoplastic Agents