Lanthanide-mediated phosphoester hydrolysis and phosphate elimination from phosphopeptides

Chem Commun (Camb). 2005 Nov 21:(43):5426-8. doi: 10.1039/b510123a. Epub 2005 Sep 30.

Abstract

Lanthanide ions can mediate both phosphomonoester hydrolysis and beta-elimination of inorganic phosphate from polypeptide substrates under near-physiological conditions of pH, temperature, and salt.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemistry
  • Amino Acid Sequence
  • Esterification
  • Hydrolysis
  • Lanthanoid Series Elements / chemistry*
  • Molecular Sequence Data
  • Nucleotides / chemistry
  • Phosphates / chemistry*
  • Phosphopeptides / chemistry*
  • Phosphorylation

Substances

  • Amides
  • Lanthanoid Series Elements
  • Nucleotides
  • Phosphates
  • Phosphopeptides