Swept source optical coherence tomography using an all-fiber 1300-nm ring laser source

J Biomed Opt. 2005 Jul-Aug;10(4):44009. doi: 10.1117/1.1961474.

Abstract

The increased sensitivity of spectral domain optical coherence tomography (OCT) has driven the development of a new generation of technologies in OCT, including rapidly tunable, broad bandwidth swept laser sources and spectral domain OCT interferometer topologies. In this work, the operation of a turnkey 1300-nm swept laser source is demonstrated. This source has a fiber ring cavity with a semiconductor optical amplifier gain medium. Intracavity mode selection is achieved with an in-fiber tunable fiber Fabry-Perot filter. A novel optoelectronic technique that allows for even sampling of the swept source OCT signal in k space also is described. A differential swept source OCT system is presented, and images of in vivo human cornea and skin are presented. Lastly, the effects of analog-to-digital converter aliasing on image quality in swept source OCT are discussed.

Publication types

  • Evaluation Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Cornea / cytology*
  • Equipment Design
  • Equipment Failure Analysis
  • Fiber Optic Technology / instrumentation*
  • Humans
  • Microscopy, Confocal / instrumentation*
  • Microscopy, Confocal / methods
  • Ophthalmoscopes*
  • Reproducibility of Results
  • Semiconductors
  • Sensitivity and Specificity
  • Skin / cytology*
  • Tomography, Optical Coherence / instrumentation*
  • Tomography, Optical Coherence / methods