Langerhans cell histiocytosis: report of a single organ involvement in a child

J Cell Mol Med. 2004 Jul-Sep;8(3):397-401. doi: 10.1111/j.1582-4934.2004.tb00329.x.

Abstract

Langerhans cell histiocytosis is a rare disorder characterized by abnormal proliferation of Langerhans cells that can affect various organ systems. The disease usually presents as a unifocal lytic bone lesion and can affect any age group. Less frequently it presents as a disseminated disease with multisystem involvement. Hepatic manifestation in Langerhans cell histiocytosis is relatively rare and usually presents as a part of a disseminated process. We report a case of Langerhans cell histiocytosis involving only the liver in a 9-years-old child.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Child
  • Female
  • Histiocytosis, Langerhans-Cell / diagnosis*
  • Histiocytosis, Langerhans-Cell / pathology
  • Humans
  • Immunohistochemistry
  • Liver / pathology*
  • Liver Cirrhosis / pathology