A new twist in the hijacking of the actin-nucleating machinery

Maria Lara-Tejero; Jorge E Galán

doi:10.1016/j.molcel.2004.08.013

A new twist in the hijacking of the actin-nucleating machinery

Mol Cell. 2004 Aug 27;15(4):495-7. doi: 10.1016/j.molcel.2004.08.013.

Authors

Maria Lara-Tejero¹, Jorge E Galán

Affiliation

¹ Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.

PMID: 15327766
DOI: 10.1016/j.molcel.2004.08.013

Abstract

Many microbial pathogens have evolved specific adaptations to harness the host cell actin cytoskeleton. The understanding of these mechanisms reveals a striking level of complexity and diversity in the strategies utilized by different pathogens to module actin dynamics.

MeSH terms

Actins / metabolism*
Cytoskeleton / metabolism
Escherichia coli Infections / metabolism*
Escherichia coli O157* / genetics
Escherichia coli O157* / metabolism
Escherichia coli O157* / pathogenicity
Genomic Islands
Humans
Nerve Tissue Proteins / metabolism
Wiskott-Aldrich Syndrome Protein, Neuronal

Substances

Actins
Nerve Tissue Proteins
WASL protein, human
Wiskott-Aldrich Syndrome Protein, Neuronal