Following short-term signs of weakness, depression, and/or anorexia of less than 24 h, two adult male African green monkeys (Cercopithecus aethiops sabeus) of St. Kitts origin died from complications of cecal volvulus. Gaseous distention was radiologically apparent in one animal. Necropsy of both monkeys revealed cecal volvulus, one at the ileocecal junction and one involving a segment of the distal portion of the ileum and cecum. Congestion and hemorrhage were evident microscopically in the lamina propria of the affected intestine, with variable necrosis.