Probing the yeast proteome for RNA-processing factors

Genome Biol. 2003;4(10):229. doi: 10.1186/gb-2003-4-10-229. Epub 2003 Sep 22.

Abstract

A method has been developed to identify proteins required for the biogenesis of non-coding RNA in yeast, using a microarray to screen for aberrant patterns of RNA processing in mutant strains, and new proteins involved in the processing of ribosomal and non-coding RNAs have been found.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Fungal Proteins / metabolism*
  • Oligonucleotide Array Sequence Analysis
  • Proteome / metabolism*
  • Proteomics* / methods
  • RNA, Untranslated / biosynthesis*
  • RNA, Untranslated / genetics
  • RNA, Untranslated / metabolism
  • Ribosomes / genetics
  • Ribosomes / metabolism

Substances

  • Fungal Proteins
  • Proteome
  • RNA, Untranslated