Abstract
A 2.5 A crystal structure of a complex between the SUMO-conjugating enzyme Ubc9 and a protein substrate has yielded fresh insight into the specificity of protein modification by SUMO and other ubiquitin-like proteins.
MeSH terms
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Crystallography, X-Ray
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Ligases / chemistry*
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Ligases / metabolism
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Macromolecular Substances
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Models, Molecular
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Protein Binding
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Protein Conformation
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Protein Structure, Tertiary*
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Small Ubiquitin-Related Modifier Proteins / chemistry*
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Small Ubiquitin-Related Modifier Proteins / metabolism
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Substrate Specificity
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Ubiquitin-Conjugating Enzymes*
Substances
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Macromolecular Substances
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Small Ubiquitin-Related Modifier Proteins
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Ubiquitin-Conjugating Enzymes
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Ligases
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ubiquitin-conjugating enzyme UBC9