Inclusion body myositis long after dermatomyositis: a report of two cases

A L McCoy; M R Bubb; P H Plotz; J C Davis

Inclusion body myositis long after dermatomyositis: a report of two cases

Clin Exp Rheumatol. 1999 Mar-Apr;17(2):235-9.

Authors

A L McCoy¹, M R Bubb, P H Plotz, J C Davis

Affiliation

¹ Arthritis and Rheumatism Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

PMID: 10342053

Abstract

Dermatomyositis, polymyositis, and inclusion body myositis are rare illnesses which appear to be distinct in clinical and pathologic features, pathogenesis, natural history, and response to therapy. We report two patients who first developed dermatomyositis, and then, after a disease-free interval of many years, developed inclusion body myositis. This may have useful therapeutic implications for patients with dermatomyositis whose illness bocomes refractory to treatment.

Publication types

Case Reports

MeSH terms

Adult
Azathioprine / therapeutic use
Creatine Kinase / blood
Dermatomyositis / complications*
Dermatomyositis / drug therapy
Dermatomyositis / enzymology
Dermatomyositis / pathology
Humans
Male
Middle Aged
Muscle, Skeletal / pathology
Myositis, Inclusion Body / complications*
Myositis, Inclusion Body / drug therapy
Myositis, Inclusion Body / enzymology
Myositis, Inclusion Body / pathology
Prednisolone / therapeutic use

Substances

Prednisolone
Creatine Kinase
Azathioprine