PubMed for id: 1655

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37596619,37013907,33909701,33169694,33097588,33042264,31870221,30484950,30419318,29642538,28557706,28244855,28216662,26314252,26212035,26080402,26035968,24910429,24035833,22810421,22750847,22640416,22476084,22156369,21345143,20124720,18698352,18239468,17724023,17540040,15927448,15113910,12101238,10648785,2451786,2349099,1996094,38040691,36282044,36246972,36044855,35549637,35184719,35007564,34697388,34021034,33634895,32228614,32008867,31445188,31267554,31015574,30720177,30506978,30387548,30185232,30119889,30042133,29227193,26739063,24626184,23322042,23108395,22086602,20818423,20022962,18829551,18794152,17699760,17384675,15950181,15304501,12595555,2762324,36997114,34890713,34308648,33819916,33550957,33108271,33068674,32920730,32747416,31994189,31626956,31387890,31379208,30281815,29540201,28411202,26312911,25745998,24219989,23741449,23143267,20676135,19718048,17369852,17018282,16697732,10837141,36012594,32724471,32463358,25604459,24644279,24275493,23349811,22222205,21343338,19626115,18005418,17960593,15298701,12665590,7774924,7525583,37793472,35604033,26587974,25963660,23482664,19171422,17696464,15660129,12527917,11279182,33754075,29212181,27338022,25701821,22266867,22210892,18279852,23608157,19995069,20966046,20663877,15596820,24910439,23022728,19224332,28111200,26965827,17011493,12738788,24581491,23788676,21900255,21994455,20856200,15464984,30792309,17765891,15846844,19917253,16230076,27365398,25882849,18954305,21911577,29474905,20308691,32939012,30179224,18548003,18377426,36266428,26469385,19596686,26420826,24140279,22963397,21575865,15782174,29846670,20080577,17267499,36252997,16611982,24147044,23658844,26030138,30320934,26362536,20890123,31160578,19928837,29934401,20085707,15047060,28137758,23254330,17932509,17220478,29162697,16226712,36095012,30559450,34244791,31751430,35102251,31527668,26990986,25662211,18809582,25670202,17361185,25144556,31267705,31280863,30459231,24965446,23151878,34445801,22446626,33087562,16791210,22079093,35896951,27129302,15840729,34383978,25948554,25071155,21942715,34462429,36055981,29511296,28416769,17332742,35583604,22944692,32905556,26979993,23874603,21280222,30320910,28977470,35676246,28225217,18457437,16055720,36490346,22751105,20508642,31332168,11991638,36470425,23184937,16159877,18624398,35198878,30711629,29777862,29449217,21907836,20195357,19454010,29872149,35546148,25192599,24244333,28927264,34185411,22174317,11790298,23463506,22365833,35785414,34091597,34226595,20020773,28443643,36243803,26641092,36964488,30349055,29884807,28902428,23125841,21182205,35652658,24189400,32698014,36199071,34702444,29911972,19380743,32433965,31010829,34244482,26816005,30745168,26725010,30585729,28533407,32041737,31501420,32929329,23979707,26209609,30737378,28561026,32235678,31665637,17620599,35562734,32529326,32786267,30425250,15592455,24332808,25324306,26549023,27545878,30344098,8889549,29331416,31059266,17643375,25852190,24625528,25814554,35182466,36537216,35338135,15635413,28065597,34650049,21081503,38172120,31239290,34795231,36180891,36168627,32344865,27503909,32457219,36042349,34901782,31300519,36912080,31995728,25437307,30940648,31324722,22623428,26831064,25737280,21549307,34728620,27591049,35676659,20467437,29844126,37616343,28977666,22268729,31048545,33644029,33239621,23443559,36057605,31180492,33742100,35819319,32780723,28380382,36180527,23602568,32994395,29955894,33022573,19738201,29802200,28302793,27025967,34857952,29298432,29676528,35906200,36517590,30575818,32129710,25963833,35850772,27609421,28986522,33916271,36574265,36373674,33306668,36424410,24711643,21900206,35446349,29845934,29180619,15146197,27684187,36526897,17353931,15342556,30804502,33545068,30463901,27173435,32694731,29229926,20360068,29467282,32687490,28515276,30948266,22863883,35509820,22681889,32513696,21145461,35013218,29395067,37689310,32807901,31980649,38113892,25921289,35563538,34373451,19056867,24457600,29117863,19946888,32814053,32707033,26673895,36114006,35256949,22658674,31091453,22939629,31586073,29507755,37827155,18029348,35831314,26344197,35944360,34079125,36215168,35271311,26496610,16344560,14702039,28514442,8889548,33961781,15489334,12477932,21873635[uid]

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Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence.

Li F, Ling X, Chakraborty S, Fountzilas C, Wang J, Jamroze A, Liu X, Kalinski P, Tang DG. Li F, et al. J Exp Clin Cancer Res. 2023 Aug 19;42(1):213. doi: 10.1186/s13046-023-02787-x. J Exp Clin Cancer Res. 2023. PMID: 37596619 Free PMC article. Review.

Hypoxia-mediated regulation of DDX5 through decreased chromatin accessibility and post-translational targeting restricts R-loop accumulation.

Leszczynska KB, Dzwigonska M, Estephan H, Moehlenbrink J, Bowler E, Giaccia AJ, Mieczkowski J, Kaminska B, Hammond EM. Leszczynska KB, et al. Mol Oncol. 2023 Jul;17(7):1173-1191. doi: 10.1002/1878-0261.13431. Epub 2023 Apr 22. Mol Oncol. 2023. PMID: 37013907 Free PMC article.

The RNA helicase DDX5 promotes viral infection via regulating N6-methyladenosine levels on the DHX58 and NFκB transcripts to dampen antiviral innate immunity.

Xu J, Cai Y, Ma Z, Jiang B, Liu W, Cheng J, Guo N, Wang Z, Sealy JE, Song C, Wang X, Li Y. Xu J, et al. PLoS Pathog. 2021 Apr 28;17(4):e1009530. doi: 10.1371/journal.ppat.1009530. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33909701 Free PMC article.

Decreased expression of DEAD-Box helicase 5 inhibits esophageal squamous cell carcinomas by regulating endoplasmic reticulum stress and autophagy.

Ma L, Zhao X, Wang S, Zheng Y, Yang S, Hou Y, Zou B, Dong L. Ma L, et al. Biochem Biophys Res Commun. 2020 Dec 17;533(4):1449-1456. doi: 10.1016/j.bbrc.2020.10.026. Epub 2020 Oct 24. Biochem Biophys Res Commun. 2020. PMID: 33169694

Low expression of DDX5 is associated with poor prognosis in patients with pancreatic ductal adenocarcinoma.

Morimachi M, Hirabayashi K, Takanashi Y, Kawanishi A, Saika T, Ueyama Y, Nakagohri T, Nakamura N, Suzuki H, Kagawa T. Morimachi M, et al. J Clin Pathol. 2021 Nov;74(11):741-745. doi: 10.1136/jclinpath-2020-207002. Epub 2020 Oct 23. J Clin Pathol. 2021. PMID: 33097588

Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma.

Mani SKK, Yan B, Cui Z, Sun J, Utturkar S, Foca A, Fares N, Durantel D, Lanman N, Merle P, Kazemian M, Andrisani O. Mani SKK, et al. Theranostics. 2020 Sep 1;10(24):10957-10972. doi: 10.7150/thno.49629. eCollection 2020. Theranostics. 2020. PMID: 33042264 Free PMC article.

DDX5 Silencing Suppresses the Migration of Basal cell Carcinoma Cells by Downregulating JAK2/STAT3 Pathway.

Quan Z, Zhang BB, Yin F, Du J, Zhi YT, Xu J, Song N. Quan Z, et al. Technol Cancer Res Treat. 2019 Jan-Dec;18:1533033819892258. doi: 10.1177/1533033819892258. Technol Cancer Res Treat. 2019. PMID: 31870221 Free PMC article.

O-GlcNAcylation promotes colorectal cancer progression by regulating protein stability and potential catcinogenic function of DDX5.

Wu N, Jiang M, Han Y, Liu H, Chu Y, Liu H, Cao J, Hou Q, Zhao Y, Xu B, Xie X. Wu N, et al. J Cell Mol Med. 2019 Feb;23(2):1354-1362. doi: 10.1111/jcmm.14038. Epub 2018 Nov 28. J Cell Mol Med. 2019. PMID: 30484950 Free PMC article.

Roles of DDX5 in the tumorigenesis, proliferation, differentiation, metastasis and pathway regulation of human malignancies.

Nyamao RM, Wu J, Yu L, Xiao X, Zhang FM. Nyamao RM, et al. Biochim Biophys Acta Rev Cancer. 2019 Jan;1871(1):85-98. doi: 10.1016/j.bbcan.2018.11.003. Epub 2018 Nov 9. Biochim Biophys Acta Rev Cancer. 2019. PMID: 30419318 Review.

DDX5 RNA Helicases: Emerging Roles in Viral Infection.

Cheng W, Chen G, Jia H, He X, Jing Z. Cheng W, et al. Int J Mol Sci. 2018 Apr 9;19(4):1122. doi: 10.3390/ijms19041122. Int J Mol Sci. 2018. PMID: 29642538 Free PMC article. Review.

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