Increased height gain of children fed a high-protein diet during convalescence from shigellosis: a six-month follow-Up study

J Nutr. 1998 Oct;128(10):1688-91. doi: 10.1093/jn/128.10.1688.

Abstract

The impact of dietary supplementation on catch-up growth was evaluated in 69 malnourished children ages 24-60 mo after recovery from shigellosis. They were fed either a high-protein (HP) diet with 15% of energy as protein, or a standard-protein (SP) diet with 7.5% energy as protein, for 3 wk in a metabolic study ward. Children were followed up bi-weekly for 6 mo by trained health assistants when anthropometric measurements and information of any illness were collected. Thirty-one children in the HP group and 28 children in the SP group completed 6-mo follow-up. The increase in height (mean +/- SD) was 5.3 +/- 1.0 cm vs. 4.1 +/- 1.1 cm for HP and SP groups, respectively (P < 0.001), whereas increase in body weight was 1.39 +/- 0.58 and 1.29 +/- 0.72 kg for children fed HP and SP, respectively (P = 0.59). The proportion of children who were severely stunted (< -2 SD height-for-age) decreased from 45 to 29% in the HP group compared to 50 to 46% in the SP group (P < 0.05) at 6-mo follow-up. The number of diarrheal episodes per child tended to be lower in the HP vs. SP than in the SP group (1.9 vs. 2.3, P = 0.41). These results demonstrate that feeding an HP diet to the malnourished children during recovery from shigellosis enhanced linear growth with a modest reduction in diarrheal morbidity during the 6-mo follow-up period.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amdinocillin Pivoxil / therapeutic use
  • Anthropometry
  • Anti-Infective Agents / therapeutic use
  • Bangladesh
  • Body Height / drug effects*
  • Child, Preschool
  • Convalescence*
  • Dietary Proteins / administration & dosage
  • Dietary Proteins / therapeutic use*
  • Dysentery, Bacillary / drug therapy
  • Dysentery, Bacillary / physiopathology*
  • Dysentery, Bacillary / prevention & control
  • Female
  • Growth / drug effects*
  • Humans
  • Male
  • Nalidixic Acid / therapeutic use
  • Nutritional Status
  • Penicillins / therapeutic use

Substances

  • Anti-Infective Agents
  • Dietary Proteins
  • Penicillins
  • Amdinocillin Pivoxil
  • Nalidixic Acid