The significance of angiogenesis in guided bone regeneration. A case report of a rabbit experiment

J Schmid; B Wallkamm; C H Hämmerle; S Gogolewski; N P Lang

doi:10.1034/j.1600-0501.1997.080311.x

The significance of angiogenesis in guided bone regeneration. A case report of a rabbit experiment

Clin Oral Implants Res. 1997 Jun;8(3):244-8. doi: 10.1034/j.1600-0501.1997.080311.x.

Authors

J Schmid¹, B Wallkamm, C H Hämmerle, S Gogolewski, N P Lang

Affiliation

¹ Department of Periodontology and Fixed Prosthodontics, University of Berne, Switzerland.

PMID: 9586469
DOI: 10.1034/j.1600-0501.1997.080311.x

Abstract

A dome-shaped bioresorbable membrane was fixed to the wounded rabbit calvaria and filled with a bioresorbable fibre conglomerate. After 4 weeks, the histologic preparation revealed an intimate spatial and temporal correlation between newly formed blood vessels and de novo extraskeletal bone formation. These observations emphasize the significance of angiogenesis in guided bone generation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Biocompatible Materials
Bone Regeneration / physiology*
Bone and Bones / blood supply*
Guided Tissue Regeneration*
Lactic Acid
Membranes, Artificial
Neovascularization, Physiologic*
Polyesters
Polymers
Rabbits
Skull / surgery

Substances

Biocompatible Materials
Membranes, Artificial
Polyesters
Polymers
Lactic Acid
poly(lactide)