Abscisic acid signaling through cyclic ADP-ribose in plants

Science. 1997 Dec 19;278(5346):2126-30. doi: 10.1126/science.278.5346.2126.

Abstract

Abscisic acid (ABA) is the primary hormone that mediates plant responses to stresses such as cold, drought, and salinity. Single-cell microinjection experiments in tomato were used to identify possible intermediates involved in ABA signal transduction. Cyclic ADP-ribose (cADPR) was identified as a signaling molecule in the ABA response and was shown to exert its effects by way of calcium. Bioassay experiments showed that the amounts of cADPR in Arabidopsis thaliana plants increased in response to ABA treatment and before ABA-induced gene expression.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Abscisic Acid / pharmacology*
  • Adenosine Diphosphate Ribose / analogs & derivatives*
  • Adenosine Diphosphate Ribose / metabolism
  • Adenosine Diphosphate Ribose / pharmacology
  • Arabidopsis / genetics
  • Arabidopsis / metabolism
  • Arabidopsis Proteins
  • Calcium / metabolism*
  • Calcium / pharmacology
  • Cyclic ADP-Ribose
  • Egtazic Acid / pharmacology
  • GTP-Binding Proteins / physiology
  • Gene Expression Regulation, Plant / drug effects
  • Genes, Reporter
  • Inositol Phosphates / pharmacology
  • Microinjections
  • Phosphoprotein Phosphatases / metabolism
  • Phosphorylation
  • Phytochrome / pharmacology
  • Phytochrome A
  • Plants / genetics
  • Plants / metabolism*
  • Plants, Genetically Modified
  • Protein Kinases / metabolism
  • Second Messenger Systems*
  • Signal Transduction*
  • Solanum lycopersicum / genetics
  • Solanum lycopersicum / metabolism

Substances

  • Arabidopsis Proteins
  • Inositol Phosphates
  • PHYA protein, Arabidopsis
  • Phytochrome A
  • Phytochrome
  • Cyclic ADP-Ribose
  • Adenosine Diphosphate Ribose
  • Egtazic Acid
  • Abscisic Acid
  • Protein Kinases
  • Phosphoprotein Phosphatases
  • GTP-Binding Proteins
  • Calcium