Modulation of the autoimmune response in lupus mice by oral administration of attenuated Salmonella typhimurium expressing the IL-2 and TGF-beta genes

Ann N Y Acad Sci. 1997 Apr 5:815:499-502. doi: 10.1111/j.1749-6632.1997.tb52114.x.

Authors

M L Huggins¹, F P Huang, D Xu, G Lindop, D I Stott

Affiliation

¹ University Department of Immunology, United Kingdom.

PMID: 9186709
DOI: 10.1111/j.1749-6632.1997.tb52114.x

No abstract available

MeSH terms

Administration, Oral
Animals
Autoimmunity / drug effects*
Genetic Therapy
Genetic Vectors
Interleukin-2 / genetics*
Lupus Erythematosus, Systemic / immunology*
Lupus Erythematosus, Systemic / therapy
Mice
Mice, Inbred MRL lpr
Salmonella typhimurium
T-Lymphocytes / cytology
T-Lymphocytes / drug effects
Transfection
Transforming Growth Factor beta / genetics*

Substances

Interleukin-2
Transforming Growth Factor beta