The syndrome of lethal catatonia

Singapore Med J. 1995 Aug;36(4):400-2.

Abstract

Lethal catatonia (LC) is a life-threatening neuropsychiatric syndrome associated with a host of psychiatric, neurologic and medical conditions. The clinical picture is characterised by fragmented psychotic symptoms, catatonic phenomena particularly alternating stupor and agitation, altered consciousness, hyperthermia and other autonomic disturbances. A case of LC in a 19-year-old Chinese woman showing a dramatic response to lorazepam and bromocriptine is described and a brief overview of the contemporary literature is provided.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bromocriptine / therapeutic use
  • Catatonia / diagnosis*
  • Catatonia / drug therapy
  • Catatonia / psychology
  • Diagnosis, Differential
  • Dopamine Agonists / therapeutic use
  • Female
  • Humans
  • Hypnotics and Sedatives / therapeutic use
  • Lorazepam / therapeutic use
  • Neurocognitive Disorders / diagnosis*
  • Neurocognitive Disorders / drug therapy
  • Neurocognitive Disorders / psychology
  • Patient Care Team

Substances

  • Dopamine Agonists
  • Hypnotics and Sedatives
  • Bromocriptine
  • Lorazepam