Ofloxacin eardrop treatment for active chronic suppurative otitis media: prospective randomized study

Am J Otol. 1994 Sep;15(5):670-3.

Abstract

This report presents a prospective randomized study of 0.3 percent ofloxacin eardrops for the treatment of active chronic suppurative otitis media. Twenty-nine patients were treated with ofloxacin eardrops for 1 week, and another 27 patients were treated with Augmentin for 1 week. One week after completion of treatment, 22 (76%) patients of the group treated with ofloxacin had dry ears, and only seven (26%) patients treated with Augmentin had dry ears. Ofloxacin eardrops were effective in the initial treatment of active chronic suppurative otitis media.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Oral
  • Adolescent
  • Adult
  • Aged
  • Amoxicillin / therapeutic use
  • Amoxicillin-Potassium Clavulanate Combination
  • Anti-Infective Agents / therapeutic use*
  • Chronic Disease
  • Clavulanic Acids / therapeutic use
  • Drug Therapy, Combination / therapeutic use*
  • Female
  • Humans
  • Instillation, Drug
  • Male
  • Middle Aged
  • Ofloxacin / therapeutic use*
  • Otitis Media, Suppurative / drug therapy*
  • Otitis Media, Suppurative / microbiology
  • Prospective Studies
  • Severity of Illness Index

Substances

  • Anti-Infective Agents
  • Clavulanic Acids
  • Amoxicillin-Potassium Clavulanate Combination
  • Amoxicillin
  • Ofloxacin