Successful treatment of amoebic meningoencephalitis in a Chinese living in Hong Kong

Clin Neurol Neurosurg. 1993 Sep;95(3):249-52. doi: 10.1016/0303-8467(93)90132-z.

Abstract

Primary amoebic meningoencephalitis due to Naegleria fowleri was found in a 38-year-old Chinese man living in Hong Kong who presumably acquired the infection from swimming in a hot spring in neighbouring China. Amoebic cysts were identified in tissue taken from a brain abscess. The patient responded to surgical drainage and a 6-week course of amphotericin B, rifampicin and chloramphenicol. This is one of 6 cases of successful treatment of primary amoebic meningoencephalitis documented in the medical literature.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amebiasis / diagnosis
  • Amebiasis / drug therapy
  • Amebiasis / surgery*
  • Amphotericin B / administration & dosage
  • Animals
  • Brain Abscess / diagnosis
  • Brain Abscess / drug therapy
  • Brain Abscess / surgery*
  • Chloramphenicol / administration & dosage
  • Combined Modality Therapy
  • Craniotomy
  • Drainage
  • Drug Therapy, Combination
  • Hong Kong
  • Humans
  • Male
  • Meningoencephalitis / diagnosis
  • Meningoencephalitis / drug therapy
  • Meningoencephalitis / surgery*
  • Naegleria fowleri* / drug effects
  • Naegleria fowleri* / ultrastructure
  • Rifampin / administration & dosage

Substances

  • Chloramphenicol
  • Amphotericin B
  • Rifampin