Abstract
Primary amoebic meningoencephalitis due to Naegleria fowleri was found in a 38-year-old Chinese man living in Hong Kong who presumably acquired the infection from swimming in a hot spring in neighbouring China. Amoebic cysts were identified in tissue taken from a brain abscess. The patient responded to surgical drainage and a 6-week course of amphotericin B, rifampicin and chloramphenicol. This is one of 6 cases of successful treatment of primary amoebic meningoencephalitis documented in the medical literature.
MeSH terms
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Adult
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Amebiasis / diagnosis
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Amebiasis / drug therapy
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Amebiasis / surgery*
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Amphotericin B / administration & dosage
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Animals
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Brain Abscess / diagnosis
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Brain Abscess / drug therapy
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Brain Abscess / surgery*
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Chloramphenicol / administration & dosage
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Combined Modality Therapy
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Craniotomy
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Drainage
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Drug Therapy, Combination
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Hong Kong
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Humans
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Male
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Meningoencephalitis / diagnosis
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Meningoencephalitis / drug therapy
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Meningoencephalitis / surgery*
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Naegleria fowleri* / drug effects
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Naegleria fowleri* / ultrastructure
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Rifampin / administration & dosage
Substances
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Chloramphenicol
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Amphotericin B
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Rifampin