Abstract
High-strength pancreatic enzymes have recently been implicated as a cause of colonic strictures in children with cystic fibrosis (CF). We report a 5-year-old boy with CF who had a stricture of the hepatic flexure region with associated narrowing due to submucosal fibrosis of the transverse colon, secondary to high-lipase pancreatin therapy.
MeSH terms
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Child, Preschool
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Colon / diagnostic imaging
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Colon / pathology*
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Colonic Diseases / chemically induced*
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Colonic Diseases / diagnostic imaging
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Cystic Fibrosis / drug therapy*
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Fibrosis
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Follow-Up Studies
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Humans
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Intestinal Obstruction / chemically induced*
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Intestinal Obstruction / diagnostic imaging
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Male
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Pancreatin / adverse effects*
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Pancreatin / therapeutic use
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Radiography