Clinical manifestations of neurofibromatosis-1 in Chinese children

Pediatr Neurol. 1994 Nov;11(4):301-7. doi: 10.1016/0887-8994(94)90006-x.

Abstract

The complications of 50 Chinese children with neurofibromatosis-1 were found to be different from other ethnic groups. There was a predominance of scoliosis, speech problems, and blood malignancies, but brain tumors were rare. The majority had good prognosis. Clinical manifestations depend on the age of ascertainment and, therefore, the prediction of associated complications should be made accordingly.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Cross-Cultural Comparison*
  • Female
  • Follow-Up Studies
  • Hong Kong
  • Humans
  • Infant
  • Male
  • Neurofibromatosis 1 / diagnosis*
  • Neurofibromatosis 1 / ethnology
  • Neurofibromatosis 1 / genetics
  • Neurologic Examination
  • Phenotype