We examined the relationship between the number of autistic patients, obtained from the register of the National Autism Society (NAS), born each month between January 1953 and December 1988 in England, and the occurrence of influenza epidemics one to nine months before birth. The relative risk of developing autism, for exposure to influenza during gestation, was assessed by a Poisson regression model. Our results indicate that exposure to influenza epidemics during gestation is not associated with autism.