Abstract
A 32-year-old Chinese woman with bilateral occipital aspergilloma was treated successfully with high dose ketoconazole (1200 mg/day) for six months in conjunction with amphotericin B and 5-fluorocytosine. No unacceptable side effects occurred. The use of high dose ketoconazole could be considered in CNS aspergillosis unresponsive to conventional anti-fungal therapy.
MeSH terms
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Adult
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Amphotericin B / therapeutic use
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Aspergillosis / diagnostic imaging
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Aspergillosis / drug therapy*
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Brain Diseases / drug therapy*
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Brain Diseases / microbiology
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Drug Therapy, Combination
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Female
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Flucytosine / therapeutic use
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Hong Kong
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Humans
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Ketoconazole / administration & dosage
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Ketoconazole / therapeutic use*
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Tomography, X-Ray Computed
Substances
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Amphotericin B
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Flucytosine
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Ketoconazole