Abstract
Introduction:
Although fecal microbiota transplantation (FMT) is a recommended, clinically efficacious, and cost-effective treatment for recurrent Clostridioides difficile infection (CDI), the scale of FMT use in the United States is unknown.
Methods:
We developed a population-level CDI model.
Results:
We estimated that 48,000 FMTs could be performed annually, preventing 32,000 CDI recurrences.
Discussion:
Improving access to FMT could lead to tens of thousands fewer C. difficile episodes per year.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Clostridium Infections / diagnosis
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Clostridium Infections / epidemiology
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Clostridium Infections / therapy*
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Computer Simulation
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Fecal Microbiota Transplantation / statistics & numerical data*
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Health Services Accessibility / organization & administration*
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Health Services Accessibility / statistics & numerical data
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Humans
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Models, Statistical
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Professional Practice Gaps / statistics & numerical data*
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Recurrence
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Secondary Prevention / methods
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Secondary Prevention / organization & administration*
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Secondary Prevention / statistics & numerical data
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Treatment Outcome
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United States / epidemiology