Abstract
Molecular tubes with hydrogen bonding donors in their deep hydrophobic cavities are able to selectively bind organophosphorus compounds in water through hydrogen bonding and the hydrophobic effect. They can also be used as a fluorescent sensor for nerve agent simulants and as an inhibitor to reduce the toxicity of paraoxon to acetylcholinesterase.
MeSH terms
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Acetylcholinesterase / drug effects*
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Calorimetry
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Cholinesterase Inhibitors / chemistry*
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Cholinesterase Inhibitors / toxicity*
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Fluorescent Dyes / chemistry
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Hydrogen Bonding
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Hydrophobic and Hydrophilic Interactions
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Magnetic Resonance Spectroscopy / methods
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Nerve Agents / chemistry*
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Nerve Agents / toxicity*
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Paraoxon / chemistry*
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Paraoxon / toxicity*
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Thermodynamics
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Water / chemistry
Substances
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Cholinesterase Inhibitors
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Fluorescent Dyes
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Nerve Agents
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Water
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Acetylcholinesterase
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Paraoxon