Insulin-like growth factor levels and chronic lymphocytic leukaemia: results from the MCC-Spain and EpiLymph-Spain studies

Delphine Casabonne; Yolanda Benavente; Laura Costas; Claudia Robles; Eva Gonzalez-Barca; Esmeralda de la Banda; Esther Alonso; Marta Aymerich; Elías Campo; Rafael Marcos-Gragera; Adonina Tardón; Rocío Olmedo-Requena; Eva Gimeno; Alba Martínez-López; Oriol Casanovas; Gemma Castaño-Vinyals; Nuria Aragonés; Marina Pollán; Manolis Kogevinas; Silvia de Sanjosé

doi:10.1111/bjh.15583

Insulin-like growth factor levels and chronic lymphocytic leukaemia: results from the MCC-Spain and EpiLymph-Spain studies

Br J Haematol. 2019 May;185(3):608-612. doi: 10.1111/bjh.15583. Epub 2018 Nov 19.

Authors

Delphine Casabonne^{1

2}, Yolanda Benavente^{1

2}, Laura Costas¹, Claudia Robles¹, Eva Gonzalez-Barca³, Esmeralda de la Banda⁴, Esther Alonso⁴, Marta Aymerich⁵, Elías Campo^{5

6}, Rafael Marcos-Gragera⁷, Adonina Tardón⁸, Rocío Olmedo-Requena^{2

9

10}, Eva Gimeno¹¹, Alba Martínez-López¹², Oriol Casanovas¹², Gemma Castaño-Vinyals^{2

13

14

15}, Nuria Aragonés^{2

16}, Marina Pollán^{2

17

18}, Manolis Kogevinas^{2

13

14

15}, Silvia de Sanjosé^{1

2

19}

Affiliations

¹ Unit of Infections and Cancer. Cancer Epidemiology Research Programme. IDIBELL, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Spain.
² Centro de Investigación Biomédica en Red: Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
³ Haematology, IDIBELL, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Spain.
⁴ Department of Pathology, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain.
⁵ Haematopathology Unit, Pathology Department, Hospital Clínic, University of Barcelona, Institute of Biomedical Research August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
⁶ Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
⁷ Unitat d'Epidemiologia i Registre de Càncer de Girona (UERCG), Pla Director d'Oncologia, Institut Català d'Oncologia. Institut d'Investigació Biomèdica de Girona (IdIBGi), Universitat de Girona, Girona, Spain.
⁸ IUOPA, Universidad de Oviedo, Asturias, Spain.
⁹ Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain.
¹⁰ Instituto de Investigación Biosanitaria de Granada, Hospitales Universitarios de Granada, Granada, Spain.
¹¹ Department of Clinical Haematology, Hospital del Mar, Barcelona, Spain.
¹² Tumuor Angiogenesis Group, Catalan Institute of Oncology (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
¹³ ISGlobal, Barcelona, Spain.
¹⁴ Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
¹⁵ Universitat Pompeu Fabra (UPF), Barcelona, Spain.
¹⁶ Epidemiology Section, Public Health Division, Department of Health of Madrid, Madrid, Spain.
¹⁷ Cancer and Environmental Epidemiology Unit, National Centre for Epidemiology, Carlos III Institute of Health, Madrid, Spain.
¹⁸ Cancer Epidemiology Research Group, Oncology and Haematology Area, IIS Puerta de Hierro (IDIPHIM), Madrid, Spain.
¹⁹ Reproductive Health, Foundation for Appropriate Technologies in Health (PATH), Seattle, US.

PMID: 30450673
DOI: 10.1111/bjh.15583

No abstract available

Keywords: Chronic lymphocytic leukaemia; body mass index; insulin-like growth factor 1; insulin-like growth factor binding protein 3; plasma.

Publication types

Clinical Trial
Letter
Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Biomarkers, Tumor / blood*
Female
Humans
Insulin-Like Growth Factor Binding Protein 3 / blood*
Insulin-Like Growth Factor I / metabolism*
Leukemia, Lymphocytic, Chronic, B-Cell / blood*
Male
Neoplasm Proteins / blood*
Spain

Substances

Biomarkers, Tumor
IGF1 protein, human
IGFBP3 protein, human
Insulin-Like Growth Factor Binding Protein 3
Neoplasm Proteins
Insulin-Like Growth Factor I