Oncology in nephrology comes of age: A focus on chronic dialysis patients

Nephrology (Carlton). 2019 Apr;24(4):380-386. doi: 10.1111/nep.13525.

Abstract

Dialysis is the commonest modality of renal replacement therapy for patients suffering from end-stage kidney disease. Different registry studies showed that the risks of overall cancer occurrence were significantly higher in chronic dialysis patients than in the age-matched general population. However, the frequency and pattern of different cancers may vary among different geographical areas. Since chronic dialysis patients tend to have multiple comorbidities and a shorter life expectancy, routine cancer screening in all dialysis patients may not be cost-effective; rather screening should be personalized according to the patient's expected survival, candidacy for kidney transplant together with patient preferences.

Keywords: cancer; dialysis; kidney disease.

Publication types

  • Review

MeSH terms

  • Humans
  • Kidney Failure, Chronic / diagnosis
  • Kidney Failure, Chronic / epidemiology
  • Kidney Failure, Chronic / mortality
  • Kidney Failure, Chronic / therapy*
  • Kidney Transplantation
  • Medical Oncology / methods*
  • Neoplasms / diagnosis
  • Neoplasms / epidemiology*
  • Neoplasms / mortality
  • Neoplasms / surgery
  • Nephrology / methods*
  • Renal Dialysis / adverse effects*
  • Renal Dialysis / mortality
  • Risk Assessment
  • Risk Factors
  • Treatment Outcome