Adolescent-Onset Hidradenitis Suppurativa: Prevalence, Risk Factors and Disease Features

Dermatology. 2019;235(1):45-50. doi: 10.1159/000493465. Epub 2018 Oct 26.

Abstract

Background/aims: Hidradenitis suppurativa (HS) is a chronic inflammatory and destructive skin disorder. Early diagnosis and treatment are critical to stop its progression. Data concerning adolescent-onset HS are scarce. The aims of this study are to describe the prevalence of adolescent-onset HS and to explore potential risk factors and the disease features of these patients.

Patients and methods: A cross-sectional study including 134 patients was performed.

Results: Adolescent-onset HS occurred in 51.5% (69/134) of patients. Adolescent-onset HS was associated with female sex, positive family history, presence of pilonidal sinus, acne conglobata, longer disease duration and a worse perception of disease severity.

Conclusion: Adolescent-onset HS might be more frequent than previously reported. Female sex, positive family history and the presence of elements of the follicular occlusion tetrad identify individuals with a higher risk of early onset. These patients experience a longer disease duration and perceive their disease as severer.

Keywords: Adolescent; Age of onset; Diagnosis; Epidemiological study; Hidradenitis suppurativa.

MeSH terms

  • Adolescent
  • Adult
  • Cross-Sectional Studies
  • Disease Progression
  • Female
  • Hidradenitis Suppurativa / diagnosis*
  • Hidradenitis Suppurativa / epidemiology*
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Spain / epidemiology
  • Young Adult