Growth hormone gene expression in eukaryotic cells directed by the Rous sarcoma virus long terminal repeat or cytomegalovirus immediate-early promoter

Gene. 1985;38(1-3):227-32. doi: 10.1016/0378-1119(85)90221-5.

Abstract

The cytomegalovirus (CMV) immediate-early (IE) gene-regulatory region was found to be three- to fourfold more efficient than the Rous sarcoma retroviral long terminal repeat (LTR) in promoting expression of the bovine growth hormone (bGH) gene by rat GH3 cells.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Avian Sarcoma Viruses / genetics
  • Base Sequence
  • Cattle
  • Cells, Cultured
  • Cytomegalovirus / genetics
  • DNA, Recombinant
  • Enhancer Elements, Genetic*
  • Gene Expression Regulation
  • Genes, Regulator*
  • Genetic Engineering
  • Genetic Vectors
  • Growth Hormone / genetics*
  • Promoter Regions, Genetic*
  • Rats
  • Repetitive Sequences, Nucleic Acid

Substances

  • DNA, Recombinant
  • Growth Hormone