[Review of the novelties from the 2017 ECTRIMS Congress, presented at the 10th Post-ECTRIMS Meeting (I)]

Rev Neurol. 2018 Jul 1;67(1):15-27.
[Article in Spanish]

Abstract

The Post-ECTRIMS Meeting is an emblematic event in the field of multiple sclerosis in Spain. Its chief aim is bring together the country's leading specialist neurologists to analyse the main advances made in multiple sclerosis and to review the most important topics addressed at the ECTRIMS Congress. The tenth Post-ECTRIMS Meeting was held in November 2017. Over the years this event has firmly established itself as an important meeting point where experts from all over the country get together to foster communication, establish synergies and promote and enhance research ultimately aimed at improving the prognosis and quality of life of patients with multiple sclerosis. This first part reports on the publication of the new European and American clinical guidelines on the use of disease-modifying treatments and the new diagnostic criteria. It also discusses the strategies for following up patients treated with disease-modifying therapies, reviews cerebral atrophy and biomarkers of neurodegeneration and neuroinflammation, and analyses the role of neuroglia in pathogenesis and treatment. The study examines the natural history of the disease, with the evidence provided by registers, and we anticipate the future thanks to the progress being made in genetics and immunology.

Title: Revision de las novedades del Congreso ECTRIMS 2017, presentadas en la X Reunion Post-ECTRIMS (I).

La reunion Post-ECTRIMS es una reunion emblematica en el ambito de la esclerosis multiple en España, con el claro objetivo de analizar, de la mano de reconocidos neurologos especialistas nacionales, los principales avances en esclerosis multiple y revisar los temas mas importantes del congreso ECTRIMS. En noviembre de 2017, la reunion Post-ECTRIMS celebro su decima edicion, y se ha consolidado como un importante foro de encuentro de expertos en nuestro pais para favorecer la comunicacion, establecer sinergias, y promover y potenciar la investigacion para mejorar, en ultima instancia, el pronostico y la calidad de vida de los pacientes con esclerosis multiple. En esta primera parte se avanza la publicacion de las nuevas guias clinicas europea y americana para el uso de los tratamientos modificadores de la enfermedad, y los nuevos criterios diagnosticos. Se discuten las estrategias para el seguimiento de los pacientes tratados con terapias modificadoras de la enfermedad, se revisan la atrofia cerebral y los biomarcadores de neurodegeneracion y neuroinflamacion, y se analiza el papel de la neuroglia en la patogenia y el tratamiento. Se hace un recorrido por la historia natural de la enfermedad, con la evidencia que aportan los registros, y nos adelantamos al futuro gracias a los avances en genetica e inmunologia.

Publication types

  • Review

MeSH terms

  • Atrophy / etiology
  • Atrophy / pathology
  • Autoimmunity
  • Biomarkers
  • Blood-Brain Barrier
  • Brain / pathology
  • Central Nervous System / immunology
  • Central Nervous System / physiology
  • Congresses as Topic*
  • Genetic Predisposition to Disease
  • Humans
  • Multiple Sclerosis* / diagnosis
  • Multiple Sclerosis* / genetics
  • Multiple Sclerosis* / immunology
  • Multiple Sclerosis* / therapy
  • Nerve Regeneration
  • Neuroglia / pathology
  • Neurology*

Substances

  • Biomarkers