Use of serum squamous cell carcinoma antigen assays in chemotherapy treatment of cervical cancer

H Y Ngan; L C Wong; S Y Chan; H K Ma

doi:10.1016/0090-8258(89)90056-5

Use of serum squamous cell carcinoma antigen assays in chemotherapy treatment of cervical cancer

Gynecol Oncol. 1989 Nov;35(2):259-62. doi: 10.1016/0090-8258(89)90056-5.

Authors

H Y Ngan¹, L C Wong, S Y Chan, H K Ma

Affiliation

¹ Department of Obstetrics and Gynaecology, University of Hong Kong.

PMID: 2807021
DOI: 10.1016/0090-8258(89)90056-5

Abstract

Serum squamous cell carcinoma antigen levels of 15 patients with recurrent or progressive squamous cell carcinoma of the cervix on chemotherapy treatment were assayed. In 13 of these 15 patients (86.7%), clinical response was positive correlated with change in serum SCC level. A stationary or rising serum SCC level indicated that the disease is probably stationary or progressive and chemotherapy should be stopped or changed.

MeSH terms

Adult
Aged
Antigens, Neoplasm
Antineoplastic Agents / therapeutic use*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Cisplatin / administration & dosage
Female
Fluorouracil / administration & dosage
Humans
Lymphatic Metastasis
Middle Aged
Serpins*
Uterine Cervical Neoplasms / blood
Uterine Cervical Neoplasms / drug therapy
Uterine Cervical Neoplasms / immunology*

Substances

Antigens, Neoplasm
Antineoplastic Agents
Serpins
squamous cell carcinoma-related antigen
Cisplatin
Fluorouracil