Sex and the treatment effect in the Chinese Medicine NeuroAiD Efficacy on Stroke recovery (CHIMES) trial

Natasha L Fabiaña; Christopher L H Chen; Narayanaswamy Venketasubramanian; Chun Fan Lee; K S Lawrence Wong; Deidre Anne De Silva

doi:10.1016/j.jocn.2016.04.013

Sex and the treatment effect in the Chinese Medicine NeuroAiD Efficacy on Stroke recovery (CHIMES) trial

J Clin Neurosci. 2016 Nov:33:269-270. doi: 10.1016/j.jocn.2016.04.013. Epub 2016 Jul 25.

Authors

Natasha L Fabiaña¹, Christopher L H Chen², Narayanaswamy Venketasubramanian³, Chun Fan Lee⁴, K S Lawrence Wong⁵, Deidre Anne De Silva⁶

Affiliations

¹ Department of Neurology, National Neuroscience Institute, Singapore General Hospital Campus, 20 College Road, Singapore 169856, Singapore.
² Department of Pharmacology, National University of Singapore, #04-01, MD3, 16 Medical Dr, Singapore.
³ Raffles Neuroscience Centre, Raffles Hospital, 585 North Bridge Road, Singapore.
⁴ Singapore Clinical Research Institute, Singapore.
⁵ Department of Neurology, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
⁶ Department of Neurology, National Neuroscience Institute, Singapore General Hospital Campus, 20 College Road, Singapore 169856, Singapore. Electronic address: gnrdsd@sgh.com.sg.

PMID: 27469414
DOI: 10.1016/j.jocn.2016.04.013

Abstract

In the randomized controlled trial of NeuroAiD versus placebo following ischemic stroke, there was a trend for sex influencing the treatment effect of NeuroAiD in improving functional outcome following ischemic stroke (p=0.075).

Keywords: Sex; Stroke recovery; Traditional Chinese medicine.

Publication types

Randomized Controlled Trial

MeSH terms

Aged
Double-Blind Method
Drugs, Chinese Herbal / therapeutic use*
Female
Humans
Male
Sex Characteristics*
Stroke / drug therapy*
Treatment Outcome

Substances

Drugs, Chinese Herbal
Neuroaid