Oral feeding of minocycline attenuates glial activation and reductions of tau and drebrin in response to systemically injected cytokines

Hong Kong Med J. 2016 Jun;22(3 Suppl 4):16-21.

Authors

D Ch Poon¹, Y S Ho², C F Lau¹, K Chiu¹, R Cc Chang³

Affiliations

¹ Laboratory of Neurodegenerative Diseases, School of Biomedical Sciences, The University of Hong Kong.
² School of Nursing, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University.
³ Laboratory of Neurodegenerative Diseases, School of Biomedical Sciences; Research Centre of Heart, Brain, Hormone and Healthy Aging, LKS Faculty of Medicine; State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong.

PMID: 27390005

No abstract available

MeSH terms

Animals
Cytokines / administration & dosage
Cytokines / metabolism*
Hippocampus / drug effects*
Hippocampus / metabolism
Male
Minocycline / administration & dosage*
Minocycline / pharmacology
Neuroglia / metabolism
Neuropeptides / metabolism
Neuroprotective Agents / administration & dosage*
Neuroprotective Agents / pharmacology
Rats
Rats, Sprague-Dawley
tau Proteins / metabolism

Substances

Cytokines
Neuropeptides
Neuroprotective Agents
drebrins
tau Proteins
Minocycline