Avoiding Adverse Events Secondary to Opioid-Induced Respiratory Depression: Implications for Nurse Executives and Patient Safety

J Nurs Adm. 2016 Feb;46(2):87-94. doi: 10.1097/NNA.0000000000000301.

Abstract

Background: Guidelines with recommendations for monitoring type and timing of hospitalized patients for opioid-induced respiratory depression have been published, yet adverse events continue to occur.

Objective: This study reports on the monitoring practices of 8 hospitals that volunteered to pilot test a Centers for Medicare & Medicaid Services e-quality measure that was under development. Recommendations for nurse executives are provided to support patient safety.

Methods: Data on monitoring practices were collected retrospectively from the electronic medical records at 8 hospitals on all patients receiving intravenous (IV) opioids for more than 2.5 continuous hours via patient-controlled analgesia (PCA). Analysis included the percentage of patients who were monitored according to specific standards developed by a panel of technical experts with comparisons of naloxone use to monitoring practices.

Results: Recommended patient assessments occurred in only 8.3% of the patients. No patients who were assessed at least every 2.5 hours received naloxone.

Conclusions: Care for patients receiving IV PCA is lacking in adherence to latest safety standards. Nurse executives must implement structures and processes to promote vigilance with evidence-based monitoring practices.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Analgesics, Opioid / adverse effects*
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Medicare
  • Middle Aged
  • Pilot Projects
  • Practice Guidelines as Topic
  • Process Assessment, Health Care
  • Respiratory Insufficiency / chemically induced
  • Respiratory Insufficiency / epidemiology*
  • Respiratory Insufficiency / nursing
  • Respiratory Insufficiency / prevention & control
  • Retrospective Studies
  • Rural Health Services
  • Safety Management*
  • United States / epidemiology
  • Urban Health Services
  • Young Adult

Substances

  • Analgesics, Opioid