Abstract
Our case series showed that uncomplicated Yarrowia lipolytica fungemia might be treated with catheter removal alone. The Vitek 2 YST identification (ID) card system, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), and internal transcribed spacer and 25S nuclear ribosomal DNA (nrDNA) gene sequencing provided reliable identification. All isolates had low MICs to voriconazole, echinocandins, and amphotericin B.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.
Publication types
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Multicenter Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Amphotericin B / pharmacology
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Antifungal Agents / therapeutic use*
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Base Sequence
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Catheter-Related Infections / diagnosis*
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Catheter-Related Infections / drug therapy
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Catheter-Related Infections / microbiology
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Catheterization, Central Venous / adverse effects
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Catheterization, Peripheral / adverse effects
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Child, Preschool
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DNA, Ribosomal Spacer / genetics*
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Echinocandins / pharmacology
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Female
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Fungemia / diagnosis*
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Fungemia / drug therapy*
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Fungemia / microbiology
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Hospitalization
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Humans
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Infant
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Male
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Microbial Sensitivity Tests
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Middle Aged
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Molecular Sequence Data
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Prospective Studies
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Sequence Analysis, DNA
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Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
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Voriconazole / pharmacology
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Yarrowia / drug effects
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Yarrowia / genetics*
Substances
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Antifungal Agents
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DNA, Ribosomal Spacer
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Echinocandins
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Amphotericin B
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Voriconazole