Targeted vaccination of teenagers following continued rapid endemic expansion of a single meningococcal group W clone (sequence type 11 clonal complex), United Kingdom 2015

Euro Surveill. 2015 Jul 16;20(28):21188. doi: 10.2807/1560-7917.es2015.20.28.21188.

Abstract

Since the epidemiological year 2009/10, the United Kingdom has experienced a year-on-year increase in meningococcal group W (MenW) disease due to rapid expansion of a single endemic hyper-virulent strain belonging to sequence type 11 clonal complex (cc). This strain was identified among cases diagnosed across all regions and was not linked to travel abroad. Consequently, an adolescent MenACWY conjugate vaccination programme for 13-18 year-olds will be introduced in August 2015, with priority given to 17-18 year-olds (school leavers).

MeSH terms

  • Adolescent
  • Age Distribution
  • Antigens, Bacterial / immunology
  • Disease Outbreaks
  • Endemic Diseases
  • Epidemiological Monitoring
  • Female
  • Humans
  • Immunization Programs*
  • Male
  • Meningitis, Meningococcal / epidemiology
  • Meningitis, Meningococcal / microbiology
  • Meningitis, Meningococcal / prevention & control*
  • Meningococcal Infections / epidemiology
  • Meningococcal Infections / microbiology
  • Meningococcal Infections / prevention & control*
  • Meningococcal Vaccines / administration & dosage*
  • Neisseria meningitidis / classification*
  • Neisseria meningitidis / genetics
  • Neisseria meningitidis / isolation & purification
  • Phenotype
  • Polymerase Chain Reaction
  • United Kingdom / epidemiology
  • Vaccination / methods*
  • Vaccines, Conjugate / administration & dosage

Substances

  • Antigens, Bacterial
  • MenACWY
  • Meningococcal Vaccines
  • Vaccines, Conjugate