First Report of Human Infection by Agromyces mediolanus, a Gram-Positive Organism Found in Soil

Siddharth Sridhar; Angela Y M Wang; Jasper F W Chan; Cyril C Y Yip; Susanna K P Lau; Patrick C Y Woo; Kwok-Yung Yuen

doi:10.1128/JCM.01508-15

First Report of Human Infection by Agromyces mediolanus, a Gram-Positive Organism Found in Soil

J Clin Microbiol. 2015 Oct;53(10):3377-9. doi: 10.1128/JCM.01508-15. Epub 2015 Jul 22.

Authors

Siddharth Sridhar¹, Angela Y M Wang², Jasper F W Chan³, Cyril C Y Yip¹, Susanna K P Lau⁴, Patrick C Y Woo³, Kwok-Yung Yuen³

Affiliations

¹ Department of Microbiology, The University of Hong Kong, Hong Kong, China.
² Department of Medicine, The University of Hong Kong, Hong Kong, China.
³ Department of Microbiology, The University of Hong Kong, Hong Kong, China State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, China Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong, China.
⁴ Department of Microbiology, The University of Hong Kong, Hong Kong, China State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, China Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong, China skplau@hku.hk.

Abstract

We report the first human infection by a member of the Agromyces genus, a group of Gram-positive bacteria found in soil. A patient with a long-term venous catheter developed bacteremia due to a non-vancomycin-susceptible isolate of Agromyces mediolanus. Rapid identification was possible by matrix-assisted laser desorption ionization-time of flight mass spectrometry.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Actinobacteria / chemistry
Actinobacteria / classification
Actinobacteria / drug effects
Actinobacteria / isolation & purification*
Aged, 80 and over
Anti-Bacterial Agents / pharmacology
Bacteremia / diagnosis*
Bacteremia / microbiology
Bacteremia / pathology*
Catheter-Related Infections / diagnosis*
Catheter-Related Infections / microbiology
Catheter-Related Infections / pathology*
Cluster Analysis
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
DNA, Ribosomal / chemistry
DNA, Ribosomal / genetics
Gram-Positive Bacterial Infections / diagnosis*
Gram-Positive Bacterial Infections / microbiology
Gram-Positive Bacterial Infections / pathology*
Humans
Male
Microbial Sensitivity Tests
Microbiological Techniques
Molecular Sequence Data
Phylogeny
RNA, Ribosomal, 16S / genetics
Sequence Analysis, DNA
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Substances

Anti-Bacterial Agents
DNA, Bacterial
DNA, Ribosomal
RNA, Ribosomal, 16S

Associated data

GENBANK/KR780769