Abstract
We studied restriction fragment length polymorphism of the enterotoxin genes of isolates of Vibrio cholerae El Tor, indistinguishable by bacteriophage typing, which were collected in Hong Kong since 1978. Using this approach, we could distinguish indigenous and exogenous strains obtained from different sources and epidemiological settings.
MeSH terms
-
Autoradiography
-
Bacteriophage Typing
-
Blotting, Southern
-
Cholera / epidemiology*
-
Cholera / microbiology
-
DNA Probes
-
DNA, Bacterial / genetics*
-
Electrophoresis, Agar Gel
-
Hong Kong
-
Humans
-
Nucleic Acid Hybridization
-
Polymorphism, Genetic*
-
Polymorphism, Restriction Fragment Length*
-
Restriction Mapping
-
Sequence Homology, Nucleic Acid
-
Vibrio cholerae / classification
-
Vibrio cholerae / genetics*
Substances
-
DNA Probes
-
DNA, Bacterial