Catheter ablation for asymptomatic atrial fibrillation?

Expert Rev Cardiovasc Ther. 2015 Mar;13(3):243-8. doi: 10.1586/14779072.2015.1011128. Epub 2015 Feb 10.

Abstract

Ablation therapy for atrial fibrillation (AF) has been shown to be more efficient than medical treatment alone. Long-term success of AF ablation is still around 50% after one ablation and higher after two, with a substantial amount of asymptomatic recurrences in formerly symptomatic patients. Given the lack of evidence for superiority of rhythm control over rate control in terms of stroke reduction and mortality, AF ablation remains a treatment for symptom reduction only, although ablation has never been a part of these studies. There is early evidence that ablation could decrease the long-term risk of stroke; however, prospective studies are needed to assess whether this is the case and how patients with a successful ablation can be identified. If AF ablation can be shown to improve long-term morbidity, it could also become a reasonable treatment for patients with asymptomatic AF.

Keywords: ablation; anticoagulation; atrial fibrillation; outcome; stroke.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Atrial Fibrillation / complications
  • Atrial Fibrillation / physiopathology
  • Atrial Fibrillation / therapy*
  • Catheter Ablation / methods*
  • Humans
  • Recurrence
  • Risk
  • Stroke / etiology
  • Stroke / prevention & control*
  • Time Factors