Do medical homes increase medication adherence for persons with multiple chronic conditions?

Med Care. 2015 Feb;53(2):168-76. doi: 10.1097/MLR.0000000000000292.

Abstract

Background: Medications are an integral component of management for many chronic conditions, and suboptimal adherence limits medication effectiveness among persons with multiple chronic conditions (MCC). Medical homes may provide a mechanism for increasing adherence among persons with MCC, thereby enhancing management of chronic conditions.

Objective: To examine the association between medical home enrollment and adherence to newly initiated medications among Medicaid enrollees with MCC.

Research design: Retrospective cohort study comparing Community Care of North Carolina medical home enrollees to nonenrollees using merged North Carolina Medicaid claims data (fiscal years 2008-2010).

Subjects: Among North Carolina Medicaid-enrolled adults with MCC, we created separate longitudinal cohorts of new users of antidepressants (N=9303), antihypertensive agents (N=12,595), oral diabetic agents (N=6409), and statins (N=9263).

Measures: Outcomes were the proportion of days covered (PDC) on treatment medication each month for 12 months and a dichotomous measure of adherence (PDC>0.80). Our primary analysis utilized person-level fixed effects models. Sensitivity analyses included propensity score and person-level random-effect models.

Results: Compared with nonenrollees, medical home enrollees exhibited higher PDC by 4.7, 6.0, 4.8, and 5.1 percentage points for depression, hypertension, diabetes, and hyperlipidemia, respectively (P's<0.001). The dichotomous adherence measure showed similar increases, with absolute differences of 4.1, 4.5, 3.5, and 4.6 percentage points, respectively (P's<0.001).

Conclusions: Among Medicaid enrollees with MCC, adherence to new medications is greater for those enrolled in medical homes.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Antidepressive Agents / therapeutic use
  • Chronic Disease / drug therapy*
  • Cohort Studies
  • Depression / drug therapy
  • Female
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
  • Hyperlipidemias / drug therapy
  • Hypertension / drug therapy
  • Male
  • Medicaid / statistics & numerical data*
  • Medication Adherence / statistics & numerical data*
  • Medication Therapy Management / organization & administration*
  • Middle Aged
  • North Carolina
  • Patient-Centered Care / organization & administration*
  • Patient-Centered Care / statistics & numerical data*
  • Retrospective Studies
  • United States

Substances

  • Antidepressive Agents
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors