Evaluation of commercially available serologic diagnostic tests for chikungunya virus

Emerg Infect Dis. 2014 Dec;20(12):2129-32. doi: 10.3201/eid2012.141269.

Abstract

Chikungunya virus (CHIKV) is present or emerging in dengue virus-endemic areas. Infections caused by these viruses share some common signs/symptoms, but prognosis, patient care, and persistent symptoms differ. Thus, accurate diagnostic methods are essential for differentiating the infections. We evaluated 4 CHIKV serologic diagnostic tests, 2 of which showed poor sensitivity and specificity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chikungunya Fever / diagnosis*
  • Chikungunya virus / classification*
  • Enzyme-Linked Immunosorbent Assay / methods
  • Enzyme-Linked Immunosorbent Assay / standards
  • Humans
  • Reagent Kits, Diagnostic* / standards
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Serologic Tests / methods*
  • Serologic Tests / standards

Substances

  • Reagent Kits, Diagnostic